Spatiotemporal Evolution of Erythema Migrans, the Hallmark Rash of Lyme Disease
نویسندگان
چکیده
منابع مشابه
Spatiotemporal evolution of erythema migrans, the hallmark rash of Lyme disease.
To elucidate pathogen-host interactions during early Lyme disease, we developed a mathematical model that explains the spatiotemporal dynamics of the characteristic first sign of the disease, a large (≥5-cm diameter) rash, known as an erythema migrans. The model predicts that the bacterial replication and dissemination rates are the primary factors controlling the speed that the rash spreads, w...
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Background: With the recent discoveries of Borrelia burgdorferi and other spirochetes in the brains of Alzheimer’s patients and with a recent analysis showing the very same pathology in both syphilitic and Alzheimer’s dementia it seems both rational and urgent to consider all aspects of Lyme disease in a new light, especially the concept of “overdiagnosis”. The very presence of the organisms in...
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A 22-year-old woman was admitted to the hospital with fevers, neck pain, the “worst headache of her life,” and bilateral knee pain. The patient reported a history of uveitis and recounted a recent tick exposure. Physical examination revealed multiple red, circular, nonpruritic skin lesions with bull’s-eye appearances that were approximately 2 inches in diameter and located on the patient’s legs...
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1. Price RN, Uhlemann AC, Brockman A, McReady R, Ashley E, Phaipun L, et al. Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number. Lancet. 2004;364: 438–47. http://dx.doi.org/10.1016/S01406736(04)16767-6 2. Basco LK, Le Bras J, Rhoades Z, Wilson CM. Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa. Mol B...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.3211